UC- II®

Undenatured Type-II Collagen by Lonza, branded as UC-II®, a patented, undenatured form of Type II collagen that retains its natural structure, enabling it to deliver powerful joint benefits at a remarkably low dose. Clinical studies demonstrate that a 40 mg daily dose improves joint comfort, mobility, and flexibility, outperforming glucosamine + chondroitin in some trials. 

Undenatured Type II Collagen- derived from chicken sternum cartilage is a clinically studied form of collagen that works with your immune system—rather than simply replacing collagen in the body. Unlike hydrolyzed collagens that break down during digestion, UC-II® remains intact, it preserves the native triple-helix structure via a low-temperature, non-enzymatic process. This intact structure allows it to support a unique mechanism called oral tolerance, helping the body modulate its immune response and promote cartilage repair —supporting comfort, flexibility, and mobility from within.