UC- II
  • Joint

UC- II

Undenatured Type-II Collagen by Lonza, branded as UC-II®, a patented, undenatured form of Type II collagen that retains its natural structure, enabling it to deliver powerful joint benefits at a remarkably low dose. Clinical studies demonstrate that a 40 mg daily dose improves joint comfort, mobility, and flexibility, outperforming glucosamine + chondroitin in some trials. Undenatured Type II Collagen- derived from chicken sternum cartilage is a clinically studied form of collagen that works with your immune system—rather than simply replacing collagen in the body. Unlike hydrolyzed collagens that break down during digestion, UC-II® remains intact, it preserves the native triple-helix structure via a low-temperature, non-enzymatic process. This intact structure allows it to support a unique mechanism called oral tolerance, helping the body modulate its immune response and promote cartilage repair —supporting comfort, flexibility, and mobility from within. 

Origin

USA

Supplier

Lonza

Benefits

  • 15X better range of motion when compared to placebo 
  • Improved knee extension by 10% compared with baseline in the UC-II® group 
  • Supports Joint flexibility 
  • Help joints feel 10yrs younger 
  • Helps consumers meet their daily step goals 
  • Clinically Proven to have better efficacy than glucosamine + chondroitin 
  • Improves knee function in healthy individuals

Certification 1
Certification 1

Rooted in Facts, Not Fiction

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2022

UC-II® Undenatured Type II Collagen for Knee Joint Flexibility: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study

Journal of Integrative and Complementary Medicine

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2019

Associated strengthening exercises to undenatured oral type II collagen (UC-II®)

Muscles Ligaments Tendons Journal, 10(3), 481-492

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2022

Efficacy of UC-II® undenatured type II collagen on knee joint function in healthy subjects

Journal of Clinical Trials

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